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Mevidalen

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SI-5501

Mevidalen, >98% (HPLC)

CAS No. : [1638667-79-4]

Synonyms : LY3154207

IUPAC Name : 2-(2,6-Dichlorophenyl)-1-((1S,3R)-5-(3-hydroxy-3-methylbutyl)-3-(hydroxymethyl)-1-methyl-3,4-dihydroisoquinolin-2(1H)-yl)ethan-1-one

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
10MGRequest A Quote
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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
We accept
Note: Mevidalenis not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C24H29Cl2NO3
Mol. Weight :
450.40
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Mevidalen is a potent, subtype selective, and orally available human dopamine D1 receptor positive allosteric modulator (PAM) with minimal allosteric agonist activity (EC50=3 nM). Mevidalen is being developed for the potential treatment of Alzheimer's disease.

References : Hao J. et al.: J. Med Chem., 62(19), 8711-8732, 2019; Biglan K. et al.: Mov Disord., 37(3), 513-524, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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