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CAS No. : [1816989-16-8]
Synonyms : SY-1365
IUPAC Name : N-((1S,3R)-3-((5-Chloro-4-(1H-indol-3-yl)pyrimidin-2-yl)amino)-1-methylcyclohexyl)-5-((E)-4-(dimethylamino)but-2-enamido)picolinamide
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C31H35ClN8O2 | Mol. Weight : 587.13 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Mevociclib selectively targets CDK7 with strong potency (Ki = 17.4 nM) and elicits marked anti‑proliferative and apoptotic responses in solid tumor cell lines. Its broad antitumor activity spans hematologic malignancies and multiple aggressive solid tumors, highlighting its relevance in CDK7‑driven oncology research.
References : Hu S. et al.: Cancer Res., 79(13), 3479-3491, 2019.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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