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SI-6981

Miglustat, >98% (HPLC)

CAS No. : [72599-27-0]

Synonyms : N-Butyldeoxynojirimycin; NB-DNJ; OGT-918

IUPAC Name : (2R,3S,4S,5R)-1-Butyl-2-(hydroxymethyl)piperidine-3,4,5-triol

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Chemical Properites
Mol. Formula :
C10H21NO4
Mol. Weight :
219.28
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Miglustat, also known as N‑Butyldeoxynojirimycin, functions as an orally active and reversible inhibitor of ceramide glucosyltransferase, reducing glycosphingolipid production. It serves as a valuable tool compound for investigating the pathophysiology and therapeutic modulation of type I Gaucher disease.

References : Dechecchi C. M. et al.: J. Cyst. Fibros 7(6), 555-65, 2008; Arcangelo G. D. et al.: Neural Plast., 3830424, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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