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Miglustat-d9 hydrochloride

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SI-6984

Miglustat-d9 hydrochloride, >98% (HPLC)

CAS No. : [1883545-57-0]

Synonyms : N-Butyldeoxynojirimycin-d9 hydrochloride; NB-DNJ-d9 hydrochloride; OGT-918-d9 hydrochloride

IUPAC Name : (2R,3S,4S,5R)-1-(Butyl-d9)-2-(hydroxymethyl)piperidine-3,4,5-triol hydrochloride

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Chemical Properites
Mol. Formula :
C10H12D9NO4 • HCl
Mol. Weight :
264.79
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Miglustat‑d9 hydrochloride is a deuterium-labelled version of Miglustat. This can be used as an analytical labelled reference standard. Miglustat hydrochloride inhibits glucosylceramide synthase and is used in GD1 research.

References : Russak E. M. et al.: Ann. Pharmacother., 53(2), 211-216, 2019; Abian O. et al.: Mol. Pharm., 8(6), 2390-7, 2011; van Giersbergen, P. L. et al.: Clin. Pharmacol., 47(10), p. 1277-82, 2007.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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