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MIK-665

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SI-5657

MIK-665, >98% (HPLC)

CAS No. : [1799631-75-6]

Synonyms : S-64315

IUPAC Name : (R)-2-((5-(3-Chloro-2-methyl-4-(2-(4-methylpiperazin-1-yl)ethoxy)phenyl)-6-(4-fluorophenyl)thieno[2,3-d]pyrimidin-4-yl)oxy)-3-(2-((2-(2-methoxyphenyl)pyrimidin-4-yl)methoxy)phenyl)propanoic acid

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Chemical Properites
Mol. Formula :
C47H44ClFN6O6S
Mol. Weight :
875.41
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MIK-665 is derived from S63845, is a myeloid cell leukemia sequence 1 (MCL1) inhibitor. MIK-665 has an IC50 of 1.81 nM for MCL1.

References : Mukherjee N. et al.: Cancers (Basel) 12(8), 2182, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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