Milademetan

SI-6500

Milademetan, >98% (HPLC)

CAS No. : [1398568-47-2]

Synonyms : DS-3032

IUPAC Name : (3'R,4'S,5'R)-N-((3R,6S)-6-Carbamoyltetrahydro-2H-pyran-3-yl)-6''-chloro-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Milademetan selectively targets MDM2 to reactivate p53 signaling, leading to G1 arrest, senescence, and apoptotic cell death. Its potency and oral activity make it valuable for AML and solid‑tumor research.

References : Gounder M. M. et al.: European Journal of Cancer, 138S2, S1–S62, 2020; Yangbing L. et al.: Arnhold V. et al.: Oncotarget, 9(2), 2304–2319, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.