Milademetan tosylate hydrate

SI-6502

Milademetan tosylate hydrate, >98% (HPLC)

CAS No. : [2095625-97-9]

Synonyms : DS-3032 tosylate hydrate; DS-3032b

IUPAC Name : (3'R,4'S,5'R)-N-((3R,6S)-6-Carbamoyltetrahydro-2H-pyran-3-yl)-6''-chloro-4'-(2-chloro-3-fluoropyridin-4-yl)-4,4-dimethyl-2''-oxodispiro[cyclohexane-1,2'-pyrrolidine-3',3''-indoline]-5'-carboxamide 4-methylbenzenesulfonate hydrate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Milademetan tosylate hydrate selectively targets MDM2 to reactivate p53 signaling, resulting in G1 cell‑cycle arrest, senescence, and apoptotic cell death. Its potency and oral activity make it valuable for investigating AML and solid‑tumor biology.

References : Gounder M. M. et al.: European Journal of Cancer, 138S2, S1–S62, 2020; Arnhold V. et al.: Oncotarget., 9(2), 2304–2319, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.