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SI-6926

Milvexian, >98% (HPLC)

CAS No. : [1802425-99-5]

Synonyms : BMS-986177; JNJ-70033093

IUPAC Name : (5R,9S)-9-(4-(5-Chloro-2-(4-chloro-1H-1,2,3-triazol-1-yl)phenyl)-6-oxopyrimidin-1(6H)-yl)-21-(difluoromethyl)-5-methyl-21H-3-aza-1(4,2)-pyridina-2(5,4)-pyrazolacyclononaphan-4-one

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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25MGRequest A Quote
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50MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C28H23Cl2F2N9O2
Mol. Weight :
626.45
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Milvexian potently and reversibly inhibits factor XIa with sub‑nanomolar affinity in humans and maintains activity across multiple preclinical species. It demonstrates strong anti‑thrombotic effects in vitro and in vivo, making it a valuable tool for investigating coagulation pathways and thrombus formation.

References :
Pancras C. W. et al.: J. Thromb. Haemost., 20(2), 399-408, 2021; Xinkang W. et al.: T. H Open., 7(2), 97-104, 2023; Wong P. et al.: Res. Pract. Thromb. Haemost., 4(1), 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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