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CAS No. : [1313881-70-7]
Synonyms : ARQ-092
IUPAC Name : 3-(3-(4-(1-Aminocyclobutyl)phenyl)-5-phenyl-3H-imidazo[4,5-b]pyridin-2-yl)pyridin-2-amine
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C27H24N6 | Mol. Weight : 432.53 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Miransertib selectively inhibits Akt1/2/3 with low‑nanomolar potency and strongly suppresses the AKT1‑E17K mutant. It is under investigation for PI3K/Akt‑driven tumors and Proteus syndrome and demonstrates additional efficacy against Leishmania, highlighting its versatility across oncology and infectious‑disease models.
References : Lapierre J. M. et al.: J. Med. Chem., 59(13), 6455-69, 2016; Devki Nandan et al.: PLoS One., 13(11), e0206920, 2018.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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