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Mitoxantrone-d8

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SL-6110

Mitoxantrone-d8, >98% (CP)

Isotopic Purity : 98 atom % D

CAS No. : [1189974-82-0]

Related CAS No. : [65271-80-9] of the unlabelled compound

Synonyms : Mitozantrone-d8

IUPAC Name : 1,4-Dihydroxy-5,8-bis((2-((2-hydroxyethyl-1,1,2,2-d4)amino)ethyl)amino)anthracene-9,10-dione

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Chemical Properites
Mol. Formula :
C22H20D8N4O6
Mol. Weight :
452.54
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Mitoxantrone-d8 is a deuterium labelled version of Mitoxantrone, which is a topoisomerase II inhibitor; also inhibits protein kinase C (PKC). Mitoxantrone is an antitumor and antibiotic drug. Also, this is a COVID-19 related research chemical.

References : Seitz M. Curr Opin Rheumatol., 11(3), 226-232, 1999; Hirata S. et al.: Arthritis Rheum., 32(9), 1065-1073, 1989; Segal R. et al.: Semin Arthritis Rheum., 20(3), 190-200, 1990; Hirata S. et al.: Arthritis Rheum., 32(9), 1065-1073, 1989; Genestier L. et al.: J. Clin Invest., 102(2), 322-328, 1998; Cronstein B. N. et al.: J. Clin Invest., 92(6), 2675-2682, 1993.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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