Mivavotinib dihydrochloride

SI-6315

Mivavotinib dihydrochloride, >98% (HPLC)

CAS No. : [1312691-41-0]

Synonyms : TAK-659 dihydrochloride; CB-659 dihydrochloride

IUPAC Name : 6-(((1R,2S)-2-Aminocyclohexyl)amino)-7-fluoro-4-(1-methyl-1H-pyrazol-4-yl)-1,2-dihydro-3H-pyrrolo[3,4-c]pyridin-3-one dihydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Mivavotinib dihydrochloride is a potent dual SYK/FLT3 inhibitor developed for hematologic malignancies. It shows strong activity against SYK‑driven B‑cell signaling and FLT3‑mutant AML, delivering robust anti‑proliferative and pro‑apoptotic effects in preclinical models. As the dihydrochloride salt, it offers improved solubility and formulation properties, making it a useful tool compound for studying SYK/FLT3‑dependent cancers and immune‑signaling pathways.

References : Lam B. et al.: Bioorg. Med. Chem. Lett., 26(24), 5947-5950, 2016; Purroy N. et al.: Oncotarget., 8(1), 742-756, 2017; Yu J. et al.: Journal of Clinical Oncology, 34(15), e14091, 2016; Cen O. et al.: mSphere., 3(4), 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.