MK-1468

SI-7412

MK-1468, >98% (HPLC)

CAS No. : [2769107-89-1]

IUPAC Name : (S)-N-(7-Chloro-6-(4-((3R,4R)-4-hydroxy-3-methyltetrahydrofuran-3-yl)piperazin-1-yl)isoquinolin-3-yl)-6-oxaspiro[2.5]octane-1-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : MK‑1468 is an orally active and BBB‑permeable inhibitor of LRRK2, a kinase implicated in the pathogenesis of Parkinson’s disease. Its selectivity and CNS exposure make it a valuable tool compound for probing LRRK2‑driven neurodegenerative pathways.

References : Kattar S. D. et al.: J. Med. Chem., 66(21), 14912-14927, 2023; Miller G. K. et al.: Toxicol. Pathol., 51(5), 232-245, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.