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MK-2048

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SI-5889

MK-2048, >98% (HPLC)

CAS No. : [869901-69-9]

MDL No. : MFCD22628847

IUPAC Name : (S)-2-(3-Chloro-4-fluorobenzyl)-8-ethyl-10-hydroxy-N,6-dimethyl-1,9-dioxo-1,2,6,7,8,9-hexahydropyrazino[1',2':1,5]pyrrolo[2,3-d]pyridazine-4-carboxamide

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Chemical Properites
Mol. Formula :
C21H21ClFN5O4
Mol. Weight :
461.88
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MK-2048 is a second generation integrase inhibitor, intended to be used against HIV infection.

References : Quashie P. K. et al.: J. Virol., 86(5), 2696-705, 2012; Van Wesenbeeck L. et al.: Antimicrob Agents Chemother., 55(1), 321-5, 2011; Bar-Magen T. et al.: J. Virol., 84(18), 9210-6, 2010; Marsden M. D. et al.: Antimicrob Agents Chemother., 55(8), 3696-702, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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