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MK-7845

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SI-7609

MK-7845, >98% (HPLC)

CAS No. : [2952554-69-5]

IUPAC Name : Methyl ((S)-1-((1S,3aR,6aS)-1-(((S)-6,6-difluoro-1-(methylamino)-1,2-dioxoheptan-3-yl)carbamoyl)hexahydrocyclopenta[c]pyrrol-2(1H)-yl)-3,3-dimethyl-1-oxobutan-2-yl)carbamate

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C24H38F2N4O6
Mol. Weight :
516.59
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MK‑7845 selectively inhibits the SARS‑CoV‑2 3CL protease through a reversible covalent mechanism, achieving an IC50 of 8.7 nM. This profile makes it a valuable tool for studying coronavirus protease function and antiviral drug development.

References : Shurtleff W. V. et al.: J. Med. Chem., 67(5), 3935-3958, 2024 .

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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