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MK-8262

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SI-6773

MK-8262, >98% (HPLC)

CAS No. : [1432054-03-9]

IUPAC Name : 4-(5-(2-((1R,5S,7aS)-1-(3,5-Bis(trifluoromethyl)phenyl)-3-oxotetrahydro-1H,3H-pyrrolo[1,2-c]oxazol-5-yl)-4-(trifluoromethyl)phenyl)-6-methoxypyridin-3-yl)-3-methylbenzoic acid

Price And Availability
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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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100MGRequest A Quote
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C35H25F9N2O5
Mol. Weight :
724.58
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MK‑8262 is an orally active CETP inhibitor exhibiting nanomolar potency (IC50= 53 nM) and a log D of 5.3. This bistrifluoromethyl analogue is a valuable tool for probing HDL/LDL regulation and mechanisms relevant to coronary heart disease.

References : Petr. Vachal. et al.: J. Med. Chem., 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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