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MLS-0045954

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SI-6551

MLS-0045954, >98% (HPLC)

IUPAC Name : 3-(2,6-Dichlorobenzyl)-N-(furan-2-ylmethyl)-3H-purin-6-amine

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C17H13Cl2N5O
Mol. Weight :
374.23
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MLS‑0045954 is a RORγ/RORγt inhibitor that suppresses IL‑17 transcriptional signaling, making it a useful probe for investigating Th17‑driven autoimmune diseases such as psoriasis, rheumatoid arthritis, and multiple sclerosis (EAE models).

References : Stanford S. M. et al.: Nat. Chem. Biol., 13(6), 624-632, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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