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MMP-7-IN-3

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SI-7405

MMP-7-IN-3, >98% (HPLC)

CAS No. : [2865097-58-9]

IUPAC Name : N5-(2-(((S)-1-(((S)-1-((S)-2-(2-Amino-2-oxoethyl)pyrrolidin-1-yl)-3,3-dimethyl-1-oxobutan-2-yl)amino)-1-oxo-3-(pyridin-4-yl)propan-2-yl)amino)-2-oxoethyl)-N2-((4-chloro-3-(trifluoromethyl)phenyl)sulfonyl)-L-glutamine

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Chemical Properites
Mol. Formula :
C34H43ClF3N7O9S
Mol. Weight :
818.26
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MMP‑7‑IN‑3 is a potent and selective MMP‑7 inhibitor that effectively blocks MMP‑7–driven fibrotic signaling. In vivo, it suppresses kidney fibrosis progression in a unilateral ureteral obstruction mouse model, supporting its utility as a targeted tool compound for studying MMP‑7‑mediated fibrotic disease.

References : Abe-Sato K. et al.: J. Med. Chem., 66(21), 14653−14668, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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