MMV048

SI-5533

MMV048, >98% (HPLC)

CAS No. : [1314883-11-8]

MDL No. : MFCD28502126

IUPAC Name : 5-(4-(Methylsulfonyl)phenyl)-6'-(trifluoromethyl)-[3,3'-bipyridin]-2-amine

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5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : MMV390048 is a representative of a new chemical class of Plasmodium PI4K inhibitor (Kdapp=0.3 µM). MMV390048 binds to the ATP binding site of Plasmodium PI4K and does not bind to other P. falciparum and human kinases apart from human PIP4K2C, thus alleviating potential kinase-mediated safety concerns. MMV390048 is an antimalarial agent.

References : Paquet T. et al.: Sci Transl Med., 9(387), pii: eaad9735, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.