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Mobocertinib

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SI-7966

Mobocertinib, >98% (HPLC)

CAS No. : [1847461-43-1]

Synonyms : TAK-788; AP-32788

IUPAC Name : Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate

Price And Availability
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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
50MGRequest A Quote
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100MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
250MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
500MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
We accept
Chemical Properites
Mol. Formula :
C32H39N7O4
Mol. Weight :
585.71
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Mobocertinib is an irreversible EGFR/HER2 inhibitor with pronounced selectivity for EGFR exon 20 insertion mutations relative to wild‑type EGFR. Its ability to suppress oncogenic EGFRex20ins signaling supports its use in NSCLC research.

References : Gonzalvez F. et al.: Cancer Discov., 11(7), 1672-1687, 2021; Han H. et al.: Cancer Res., 81(20), 5311-5324, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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