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Mobocertinib mesylate

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SI-7967

Mobocertinib mesylate, >98% (HPLC)

CAS No. : [2389149-85-1]

Synonyms : TAK-788 mesylate; AP-32788 mesylate

IUPAC Name : Isopropyl 2-((5-acrylamido-4-((2-(dimethylamino)ethyl)(methyl)amino)-2-methoxyphenyl)amino)-4-(1-methyl-1H-indol-3-yl)pyrimidine-5-carboxylate methanesulfonate

Price And Availability
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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C32H39N7O4 • CH3SO2OH
Mol. Weight :
681.81
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Mobocertinib mesylate is an irreversible EGFR/HER2 inhibitor with pronounced selectivity for EGFR exon 20 insertion mutations relative to wild‑type EGFR. Its ability to suppress oncogenic EGFRex20ins signaling supports its use in NSCLC research and other EGFR‑driven lung cancer models.

References : Gonzalvez F. et al.: Cancer Discov., 11(7), 1672-1687, 2021; Han H. et al.: Cancer Res., 81(20), 5311-5324, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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