Momelotinib

SL-9663

Momelotinib, >98%

CAS No. : [1056634-68-4]

Synonyms : CYT-387

IUPAC Name : N-(Cyanomethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Momelotinib is an ATP-competitive inhibitor of JAK1/JAK2 with IC50a of 11 nM and 18 nM,respectively. CYT387 shows much less activity against JAK3. It is used for treating myelofibrosis in adults with anemia.

References : Pardanani A. et al.: Leukemia 23(8), 1441-1445, 2009; Monaghan K. A. et al.: Leukemia 25(12), 1891-1899, 2011; Tyner J. W. et al.: Blood 115(25), 5232-5240,2010; Kitajima S. et al.: Cancer Cell 34(3), 439-452, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.