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Momelotinib amide impurity

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Momelotinib amide impurity, >98%

CAS No. : [2489681-88-9]

IUPAC Name : N-(2-Amino-2-oxoethyl)-4-(2-((4-morpholinophenyl)amino)pyrimidin-4-yl)benzamide

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Chemical Properites
Mol. Formula :
C23H24N6O3
Mol. Weight :
432.48
Appearance :
Yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Momelotinib, which is an inhibitor of JAK1/JAK2. Momelotinib is used for treating myelofibrosis in adults with anemia.

References : Pardanani A. et al.: Leukemia 23(8), 1441-1445, 2009; Monaghan K. A. et al.: Leukemia 25(12), 1891-1899, 2011; Tyner J. W. et al.: Blood 115(25), 5232-5240, 2010; Kitajima S. et al.: Cancer Cell 34(3), 439-452, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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