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SI-7975

MOMIPP, >98% (HPLC)

CAS No. : [1363421-46-8]

IUPAC Name : (E)-3-(5-Methoxy-2-methyl-1H-indol-3-yl)-1-(pyridin-4-yl)prop-2-en-1-one

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Chemical Properites
Mol. Formula :
C18H16N2O2
Mol. Weight :
292.34
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MOMIPP is a PIKfyve inhibitor that functions as a macropinocytosis inducer, disrupting endolysosomal trafficking through PIKfyve blockade. Importantly, MOMIPP is blood–brain barrier permeable, enabling central nervous system exposure and supporting its use in brain‑penetrant PIKfyve‑targeted pharmacology.

References : Colin M. et al.: et al.: Cancers (Basel), 11(3), 411, 2019; Li Z. et al.: BMC Cancer, 19(1), 77, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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