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Monochloro tafamidis impurity

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Monochloro tafamidis impurity, >98%

CAS No. : [1521571-08-3]

IUPAC Name : 2-(3-Chlorophenyl)benzo[d]oxazole-6-carboxylic acid

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Chemical Properites
Mol. Formula :
C14H8ClNO3
Mol. Weight :
273.67
Appearance :
Grey solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Tafamidis, which is a kinetic stabilizer of transthyretin (TTR) that prevents amyloidogenesis by wild-type and mutant TTRs.

References : Bulawa C. E. et al.: Proc Natl Acad Sci U S A 109(24), 9629-9634, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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