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SI-7947

Motolimod, >98% (HPLC)

CAS No. : [926927-61-9]

Synonyms : VTX-2337; VTX-378

IUPAC Name : 2-Amino-N,N-dipropyl-8-(4-(pyrrolidine-1-carbonyl)phenyl)-3H-benzo[b]azepine-4-carboxamide

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C28H34N4O2
Mol. Weight :
458.61
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Motolimod selectively activates TLR8 with an EC50of about 100 nM, stimulating innate immune responses. It is commonly used to investigate TLR8‑driven cytokine induction and immuno‑oncology mechanisms.

References : Lu H. et al.: Clin. Cancer Res., 18(2), 499-509, 2012; Dietsch G. N. et al.: PLoS One, 11(2), e0148764, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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