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CAS No. : [75438-57-2]
Synonyms : BDF5895
IUPAC Name : 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl)-6-methoxy-2-methylpyrimidin-5-amine
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 1G | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 5G | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 10G | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
| 25G | Request A Quote | In Stock | Estimated to ship on 20 September 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C9H12ClN5O | Mol. Weight : 241.68 |
Appearance : Solid | Melting Point : Not available |
Solubility : DMSO | |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : Moxonidine is an orally active imidazoline I1 receptor (I1-R) agonist that also activates α2 adrenoceptors, influencing oxidized LDL uptake. It lowers blood pressure, reduces atherosclerotic lesions, and is used to study hypertension, heart failure, and atherosclerosis.
References : Aceros H. et al.: Eur. J. Pharmacol., 740, 168-82, 2014; Wang Y. et al.: Int. J. Mol Sci., 24(4), 3857, 2023; Kim Y. H. et al.: Biochem Biophys Res Commun., 409(4), 645-50, 2011; Zhu Q. M. et al.: Br. J. Pharmacol., 126(6), 1522-30, 1999; Van Kerckhoven R. et al.: Eur. J. Pharmacol. 397(1), 113-20, 2000; Nurminen M. L. et al.: Eur. J. Pharmacol., 362(1), 61-7, 1998; Tsutsui H. et al.: Eur. J. Pharmacol., 603(1-3), 73-8, 2009.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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