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Moxonidine-d4

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SL-11105

Moxonidine-d4, >98%

CAS No. : [1794811-52-1]

Synonyms : BDF5895-d4

IUPAC Name : 4-Chloro-N-(4,5-dihydro-1H-imidazol-2-yl-4,4,5,5-d4)-6-methoxy-2-methylpyrimidin-5-amine

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Chemical Properites
Mol. Formula :
C9H8D4ClN5O
Mol. Weight :
245.7
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Moxonidine-d4 is a deuterium labelled version of Moxonidine. This can be used as an analytical labelled reference standard. Moxonidine is an orally active imidazoline I1 receptor (I1-R) agonist that also activates α2 adrenoceptors, influencing oxidized LDL uptake. Moxonidine lowers blood pressure, reduces atherosclerotic lesions, and is used to study hypertension, heart failure, and atherosclerosis.

References : Aceros H. et al.: Eur. J. Pharmacol., 740, 168-82, 2014; Wang Y. et al.: Int. J. Mol Sci., 24(4), 3857, 2023; Kim Y. H. et al.: Biochem Biophys Res Commun., 409(4), 645-50, 2011; Zhu Q. M. et al.: Br. J. Pharmacol., 126(6), 1522-30, 1999; Van Kerckhoven R. et al.: Eur. J. Pharmacol. 397(1), 113-20, 2000; Nurminen M. L. et al.: Eur. J. Pharmacol., 362(1), 61-7, 1998; Tsutsui H. et al.: Eur. J. Pharmacol., 603(1-3), 73-8, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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