MRGPRX1 agonist 4

SI-6934

MRGPRX1 agonist 4, >98% (HPLC)

CAS No. : [2764889-60-1]

IUPAC Name : 6-(tert-Butyl)-5-(3,4-dichlorophenyl)-4-(2-(trifluoromethoxy)phenoxy)thieno[2,3-d]pyrimidine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : A potent, orally active MRGPRX1 positive allosteric modulator, it shows strong activity with an EC₅₀ of 0.1 μM and exhibits good metabolic stability and oral bioavailability. In humanized MRGPRX1 neuropathic pain models, it reduces behavioral heat hypersensitivity, supporting its utility as a tool compound for neuropathic pain research.

References : Berhane I. et al.: J. Med. Chem., 65(4), 3218-3228, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.