MRT-67307 dihydrochloride

SI-7498

MRT-67307 dihydrochloride, >98% (HPLC)

CAS No. : [1781882-89-0]

IUPAC Name : N-(3-((5-Cyclopropyl-2-((3-(morpholinomethyl)phenyl)amino)pyrimidin-4-yl)amino)propyl)cyclobutanecarboxamide dihydrochloride

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : MRT-67307 dihydrochloride inhibits IKKε/TBK1 with nanomolar potency and also suppresses ULK1/ULK2 activity. By targeting both immune‑regulatory and autophagy‑initiating kinases, it robustly blocks autophagy in cells, making it a valuable tool for studying innate‑immune pathways and autophagy control.

References : Clark K. et al.: Biochem. J. 434(1), 93-104, 2011; Petherick K. J. et al.: J. Biol. Chem., 290(18), 11376-83, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.