MRTX-0902

SI-7493

MRTX-0902, >98% (HPLC)

CAS No. : [2654743-22-1]

IUPAC Name : (R)-2-Methyl-3-(1-((4-methyl-7-morpholinopyrido[3,4-d]pyridazin-1-yl)amino)ethyl)benzonitrile

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : MRTX-0902 potently inhibits SOS1 (K_i= 1.9 nM) and prevents formation of the SOS1:KRAS^G12C complex, thereby suppressing RAS activation. With strong selectivity, oral activity, and brain penetration, it serves as a valuable tool for investigating RAS‑dependent signaling in pancreatic ductal adenocarcinoma models.

References : Ketcham J. M. et al.: J. Med. Chem., 65(14), 9678-9690, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.