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MRTX-1257

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SI-6027

MRTX-1257, >98% (HPLC)

CAS No. : [2206736-04-9]

IUPAC Name : 2-((S)-1-Acryloyl-4-(7-(8-methylnaphthalen-1-yl)-2-(((S)-1-methylpyrrolidin-2-yl)methoxy)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-4-yl)piperazin-2-yl)acetonitrile

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Chemical Properites
Mol. Formula :
C33H39N7O2
Mol. Weight :
565.72
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MRTX-1257 is a selective, irreversible, covalent and orally active KRAS (G12C) inhibitor for the potential treatment of cancer.

References : Marx A. M. et al.: Mol Cancer Res., 18(5_Suppl):Abstract nr B30), 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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