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MSDC-0160

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SL-4369

MSDC-0160, >98%

CAS No. : [146062-49-9]

MDL No. : MFCD00916084

Synonyms : Pioglitazone ketone; Pioglitazone impurity; Mitoglitazone; CAY-10415

IUPAC Name : 5-(4-(2-(5-Ethylpyridin-2-yl)-2-oxoethoxy)benzyl)thiazolidine-2,4-dione

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Chemical Properites
Mol. Formula :
C19H18N2O4S
Mol. Weight :
370.42
Appearance :
Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : MSDC-0160 is a mitochondrial target of thiazolidinediones (mTOT)-modulating insulin sensitizer and a modulator of mitochondrial pyruvate carrier (MPC). MSDC 0160 is a thiazolidinedione (TZD) with antidiabetic and neuroprotective activities. MSDC-0160 has the potential for alzheimer′s disease.

References : Rohatgi N. et al.: PLoS One 8(5), e62012, 2013; Ghosh A. et al.: Sci Transl Med., 8(368), 368ra174, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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