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SI-6949

Mubritinib, >98% (HPLC)

CAS No. : [366017-09-6]

Synonyms : TAK-165

IUPAC Name : (E)-4-((4-(4-(1H-1,2,3-Triazol-1-yl)butyl)phenoxy)methyl)-2-(4-(trifluoromethyl)styryl)oxazole

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C25H23F3N4O2
Mol. Weight :
468.48
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Mubritinib selectively targets EGFR2/HER2 with nanomolar potency (IC50 = 6 nM), making it a valuable tool for probing HER2‑dependent signaling pathways and associated cancer biology.

References : Nagasawa J. et al.: Int. J. Urol., 13(5), 587-92, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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