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Mupirocin lithium

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Mupirocin lithium, >98%

CAS No. : [73346-79-9]

Synonyms : Pseudomonic acid lithium; BRL-4910A lithium

IUPAC Name : Lithium 9-(((E)-4-((2S,3R,4R,5S)-3,4-dihydroxy-5-(((2S,3S)-3-((2S,3S)-3-hydroxybutan-2-yl)oxiran-2-yl)methyl)tetrahydro-2H-pyran-2-yl)-3-methylbut-2-enoyl)oxy)nonanoate

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Chemical Properites
Mol. Formula :
C26H43LiO9
Mol. Weight :
506.56
Appearance :
Solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Mupirocin lithium is an antibiotic that inhibits bacterial isoleucyl-tRNA synthetase, preventing protein synthesis. It is highly effective against Gram-positive bacteria like Staphylococcus and Streptococcus, as well as some Gram-negative bacteria such as Haemophilus influenzae. Mupirocin lithium is used in research on skin infections (including MRSA) and chronic sinusitis.

References : Sutherland R. et al.: Antimicrob Agents Chemother., 27(4), 495-8, 1985; Parenti M. A. et al.: Clin Pharm., 6(10), 761-70, 1987; Vingsbo Lundberg C. et al.: Int J. Antimicrob Agents, 42(3), 272-5, 2013; Twilley D. et al.: Front Pharmacol., 13, 862112, 2022; Ha K. R. et al.: Laryngoscope, 118(3), 535-40, 2008; Gilbart J. et al.: Antimicrob Agents Chemother., 37(1), 32-8, 1993.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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