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Mycophenolate mofetil N-oxide

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SL-3572

Mycophenolate mofetil N-oxide, >98%

CAS No. : [224052-51-1]

Synonyms : Mycophenolate mofetil EP impurity G

IUPAC Name : (E)-4-(2-((6-(4-Hydroxy-6-methoxy-7-methyl-3-oxo-1,3-dihydroisobenzofuran-5-yl)-4-methylhex-4-enoyl)oxy)ethyl)morpholine 4-oxide

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Chemical Properites
Mol. Formula :
C23H31NO8
Mol. Weight :
449.49
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Mycophenolate mofetil N-oxide is an impurity of Mycophenolate mofetil, which is a prodrug of Mycophenolic acid. A potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation.

References : Nakanishi T. et al.: Int Immunopharmacol.,10(1), 91-97, 2010; Dehghani F. et al.: Neuropathol Appl Neurobiol., 36(7), 598-611, 2010; Ozgen M. et al.: Clin Exp Dermatol., 37(1), 48-54, 2012; Ebrahimi F. et al.: J. Neuroinflammation 9(1), 89, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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