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Mycophenolic hydroxy lactone

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Mycophenolic hydroxy lactone, >98%

CAS No. : [26644-06-4]

IUPAC Name : 7-Hydroxy-6-(2-hydroxy-2-(2-methyl-5-oxotetrahydrofuran-2-yl)ethyl)-5-methoxy-4-methylisobenzofuran-1(3H)-one

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Chemical Properites
Mol. Formula :
C17H20O7
Mol. Weight :
336.34
Appearance :
Off-white solid
Melting Point :
Not available
Solubility :
MeOH
For Laboratory research use only, not for drug, household or other uses.

Applications : Mycophenolic hydroxy lactone is an impurity of Mycophenolic acid, which is a potent IMPDH inhibitor and the active metabolite of an immunosuppressive drug, used to prevent rejection in organ transplantation.

References : Sintchak M. D. et al.: Cell., 85(6), 921-930, 1996; Eugui E. M. et al.: Scand J. Immunol., 33(2), 161-173, 1991; Anderson D. et al.: Mutat Res., 330(1-2), 115-181, 1995.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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