N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine

SI-4590

N-((3R,4R)-1-Benzyl-4-methylpiperidin-3-yl)-2-chloro-N-methyl-7H-pyrrolo[2,3-d]pyrimidin-4-amine, 97%

CAS No. : [923036-25-3]

MDL No. : MFCD23160082

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	435.00		Back Order	Estimated to ship on 04 October 2026
5G	1435.00		Back Order	Estimated to ship on 04 October 2026

Applications : This is an advanced key intermediate in the preparation of Tofacitinib and related analogs, which is a potent, specific, orally active JAK3 inhibitor, used to treat rheumatoid arthritis, psoriatic arthritis, ankylosing spondylitis and ulcerative colitis.

References : Changelian P. S. et al.: Science 302, (5646), 875-888, 2003; Jiang J. K. et al.: J. Med. Chem., 51(24), 8012-8018, 2008; Kudlacz E. et al.: Am. J. Transplant., 4(1) 51-57, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.