N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N’-propylsulfamide

SL-3519

N-[5-(4-Bromophenyl)-6-chloro-4-pyrimidinyl]-N’-propylsulfamide, >98%

CAS No. : [1393813-42-7]

IUPAC Name : 5-(4-bromophenyl)-6-chloro-N-(propylsulfamoyl)pyrimidin-4-amine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
1G	65.00		Back Order	Estimated to ship on 04 October 2026
5G	225.00		Back Order	Estimated to ship on 04 October 2026

Applications : This is an advanced keyintermediate in the preparation of Macitentan and related analogs. Macitentan is an orally active, non-peptide endothelin receptor antagonist for the treatment of idiopathic pulmonary fibrosis and pulmonary arterial hypertension.

References : Iglarz M. et al. J. Pharmacol Exp Ther., 327(3), 736-745, 2008; Sen S. et al.: Life Sci., 91(13-14), 658-668, 2012; Kim S. J. et al.: Neoplasia., 13(2), 167-179, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.