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N-Demethyl olanzapine-d8

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N-Demethyl olanzapine-d8, >98%

CAS No. : [786686-82-6]

Related CAS No. : [161696-76-0] of the unlabelled compound

IUPAC Name : 2-Methyl-4-(piperazin-1-yl-d8)-10H-benzo[b]thieno[2,3-e][1,4]diazepine

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Chemical Properites
Mol. Formula :
C16H10D8N4S
Mol. Weight :
306.46
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is the deuterium labelled version primary metabolite of Olanzapine, which is a selective, orally active atypical antipsychotic that binds with high affinity to serotonin, dopamine, muscarinic, and adrenergic α1 receptors.

References : Vucicevic L. et al.: Autophagy 10(12), 2362-78, 2014; Karpel-Massler G. et al.: J. Neurooncol., 122(1), 21-33, 2015; Coccurello R. et al.: Psychopharmacology (Berl) 186(4), 561-71, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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