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N-Demethyl vandetanib

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SL-369

N-Demethyl vandetanib, >98%

CAS No. : [338992-12-4]

MDL No. : MFCD09955369

IUPAC Name : N-(4-Bromo-2-fluorophenyl)-6-methoxy-7-(piperidin-4-ylmethoxy)quinazolin-4-amine

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG155.00
Back Order  Estimated to ship on 04 October 2026
10MG195.00
Back Order  Estimated to ship on 04 October 2026
25MG495.00
Back Order  Estimated to ship on 04 October 2026
50MG895.00
Back Order  Estimated to ship on 04 October 2026
100MG1695.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H22BrFN4O2
Mol. Weight :
461.33
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : N-Desmethyl vandetanib is the first major metabolite of vandetanib formed during the metabolism of vandetanib via cytochrome P450 (CYP) enzyme metabolism, specifically CYP3A4. The pharmacological activity of the N-desmethyl metabolite was shown to be about the same as that for vandetanib.

References : GiangThy N. T. Am. J. Health Syst. Pharm. 70(10), 849, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term storage.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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