N-Desalkyl itraconazole

SL-9561

N-Desalkyl itraconazole, >98%

CAS No. : [89848-41-9]

IUPAC Name : 4-(4-(4-(4-(((2R,4S)-2-((1H-1,2,4-Triazol-1-yl)methyl)-2-(2,4-dichlorophenyl)-1,3-dioxolan-4-yl)methoxy)phenyl)piperazin-1-yl)phenyl)-2,4-dihydro-3H-1,2,4-triazol-3-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
10MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
25MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
100MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026

Applications : This is an impurity and a metabolite of Itraconazole, which is a triazole antifungal agent known for its potent inhibition of CYP3A4. Additionally, Itraconazole acts as a potent antagonist of the Hedgehog (Hh) signalling pathway.

References : Isoherranen N. et al. Drug Metab Dispos., 32(10), 1121-1131, 2004; Kim J. et al. Cancer Cell., 17(4), 388-399, 2010; Oakley K. L. et al. Antimicrob Agents Chemother., 41(5), 1124-1126, 1997; Zuckerman J. M. et al. Infect Control Hosp Epidemiol., 15(6), 397-410, 1994; Leyden J. et al. J. Am Acad Dermatol, 38(5 Pt 3), S42-47, 1998; Isoherranen N. et al. Drug Metab Dispos., 32(10), 1121-31, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.