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N-Desbenzyl benidipine

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N-Desbenzyl benidipine, >98%

CAS No. : [758642-28-3]

IUPAC Name : 3-Methyl 5-((R)-piperidin-3-yl) (R)-2,6-dimethyl-4-(3-nitrophenyl)-1,4-dihydropyridine-3,5-dicarboxylate

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25MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
50MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
100MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
250MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
500MGRequest A Quote
In Stock  Estimated to ship on 20 September 2026
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Chemical Properites
Mol. Formula :
C21H25N3O6
Mol. Weight :
415.45
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
Acetonitrile
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Benidipine, which is a potent, orally administered calcium channel antagonist. Benidipine demonstrates anti-apoptotic properties in ischaemic or reperfused myocardial cells. Additionally, Benidipine enhances the activity of endothelial cell-type nitric oxide synthase and contributes to improved coronary circulation in hypertensive rat models.

References : Yao K. et al.: J. Pharmacol Sci., 100(4), 243-61, 2006; Gao F. et al.: Br. J. Pharmacol., 132(4), 869-78, 2001; Kobayashi N. et al.: Am. J. Hypertens 12(5), 483-91, 1999; Masanori S. et al.: Circ J. 68(3), 241-6, 2004.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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