N-Desmethyl clarithromycin

SL-4313

N-Desmethyl clarithromycin, >98%

CAS No. : [101666-68-6]

MDL No. : MFCD09840364

Synonyms : 3"-N-Demethylclarithromycin; N-(Desmethyl)clarithromycin; N-Demethylclarithromycin; USP Clarithromycin impurity D; Clarithromycin EP impurity D

IUPAC Name : (3R,4S,5S,6R,7R,9R,11R,12R,13S,14R)-14-Ethyl-12,13-dihydroxy-4-(((2R,4R,5S,6S)-5-hydroxy-4-methoxy-4,6-dimethyltetrahydro-2H-pyran-2-yl)oxy)-6-(((2S,3R,4S)-3-hydroxy-6-methyl-4-(methylamino)tetrahydro-2H-pyran-2-yl)oxy)-7-methoxy-3,5,7,9,11,13-hexamethyloxacyclotetradecane-2,10-dione; N-Demethyl-6-O-methylerythromycin

Price And Availability
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5MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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50MG	Request A Quote		In Stock	Estimated to ship on 20 September 2026
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Applications : This is an impurity or metabolite of Clarithromycin (Clarithromycin EP impurity D), which is a macrolide antibiotic and a CYP3A4 inhibitor, used to treat a number of bacterial infections.

References : Kikuchi T. et al.: J. Antimicrob Chemother, 49(5), 745-755, 2002; Ichiyama T. et al.: Antimicrob Agents Chemother, 45(1), 44-47, 2001; Khan A. A. et al.: Int. J. Antimicrob Agents, 11(2), 121-132, 1999; Abe S. et al.: Am. J. Respir Cell Mol Biol, 22(1), 51-60, 2000; Miyanohara T. et al.: Laryngoscope, 110(1), 126-131, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.