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N-Desmethyl dovitinib

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SI-6041

N-Desmethyl dovitinib, >98% (HPLC)

CAS No. : [668432-44-8]

IUPAC Name : 4-Amino-5-fluoro-3-(6-(piperazin-1-yl)-1H-benzo[d]imidazol-2-yl)quinolin-2(1H)-one

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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In Stock  Estimated to ship on 20 September 2026
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C20H19FN6O
Mol. Weight :
378.41
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : N-Desmethyl dovitinib is an analog of Dovitinib, which is an orally active, potent multi-targeted tyrosine kinase (RTK) inhibitor for the potential treatment of renal cell carcinoma (RCC).

References : Trudel S. et al.: Blood, 105(7), 2941-2948, 2005; Huynh H. et al.: J. Hepatol., 56(3), 595-601, 2012; Lee Y. et al.: Mol Cells 39(5), 389-94, 2016; Chon H. J. et al.: Amino Acids 48(7),1591-9, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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