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N-Desmethyl N-acetyl ulipristal acetate

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SL-2440

N-Desmethyl N-acetyl ulipristal acetate, >98%

CAS No. : [244206-56-2]

IUPAC Name : (8S,11R,13S,14S,17R)-17-Acetyl-13-methyl-11-(4-(N-methylacetamido)phenyl)-3-oxo-2,3,6,7,8,11,12,13,14,15,16,17-dodecahydro-1H-cyclopenta[a]phenanthren-17-yl acetate

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Chemical Properites
Mol. Formula :
C31H37NO5
Mol. Weight :
503.63
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : N-Desmethyl N-acetyl ulipristal acetate is the N-monodemethylated analog and metabolite of the Ulipristal acetate, which is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma.

References : Ciarmela P. et al.: Reprod Sci., 21(9), 1120-1125, 2014; Munuce M. J. et al.: Eur. J. Contracept Reprod Health Care. 18(5), 355-363, 2013; Pohl O. et al.: Curr Drug Saf. 8(2), 77-97, 2013; Pohl O. et al.: Regul Toxicol Pharmacol. 66(1) 6-12, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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