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N-Desmethyl tamoxifen

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SL-8974

N-Desmethyl tamoxifen, >98%

CAS No. : [31750-48-8]

IUPAC Name : (Z)-2-(4-(1,2-Diphenylbut-1-en-1-yl)phenoxy)-N-methylethan-1-amine

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We accept
Chemical Properites
Mol. Formula :
C25H27NO
Mol. Weight :
357.5
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Tamoxifen, which is a selective estrogen receptor modulator (SERM). It is used in the treatment of breast cancer. It has also been explored as a valuable research compound in studies related to COVID-19.

References : Horwitz K. B. et al.: J. Biol Chem., 253(22), 8185-91, 1978; Rondon-Lagos M. et al:. Endocr Relat Cancer., 23(8), 635-50, 2016; Zheng A. et al.: Endocrinology 148(6), 2764-77, 2007; Reinert R. B. et al.: PLoS One 7(3), e33529, 2012; Osborne C. K. et al.: J. Clin Oncol., 18(17), 3172-86, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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