N-Desmethyl thiothixene (mixture of E/Z isomers)

SL-4178

N-Desmethyl thiothixene (mixture of E/Z isomers), >98%

CAS No. : [84294-04-2]

IUPAC Name : (E/Z)-N-Methyl-9-(3-(4-methylpiperazin-1-yl)propylidene)-9H-thioxanthene-2-sulfonamide

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Applications : This is an impurity of Thiothixene, which is an antagonist of serotonergic receptor. Thiothixene is a typical antipsychotic of the thioxanthene class which is related to chlorprothixene and is used in the treatment of psychoses like schizophrenia and bipolar mania.

References : Janowsky D. et al.: J. Chlin. Psych., 67, 1272, 2006; Siegel S. et al.: Eur. J. Pharm. Bioharm., 64, 287, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.