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N-Formyl trimetazidine

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SL-4571

N-Formyl trimetazidine, >98%

CAS No. : [92700-82-8]

Synonyms : 4-[(2,3,4-Trimethoxyphenyl)methyl]-1-piperazinecarboxaldehyde; S 00218; TMZ-F

IUPAC Name : 4-(2,3,4-Trimethoxybenzyl)piperazine-1-carbaldehyde

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Chemical Properites
Mol. Formula :
C15H22N2O4
Mol. Weight :
294.35
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Trimetazidine, which is an anti-ischemic (anti-anginal) metabolic agent, which improves myocardial glucose utilization through inhibition of long-chain 3-ketoacyl CoA thiolase activity and results in a reduction in fatty acid oxidation and a stimulation of glucose oxidation.

References : Kantor P. F. et al.: Circ Res. 86(5), 580-588, 2000; Liu Z. et al.: Metabolism. 65(3), 122-130, 2016; Yang Q. et al.: Int. J. Clin Exp Pathol. 8(4), 3735-3741, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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