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N-Methyl enzalutamide

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SL-3168

N-Methyl enzalutamide, >98%

CAS No. : [1443331-78-9]

Synonyms : Enzalutamide impurity 1

IUPAC Name : 4-(3-(4-Cyano-3-(trifluoromethyl)phenyl)-5,5-dimethyl-4-oxo-2-thioxoimidazolidin-1-yl)-2-fluoro-N,N-dimethylbenzamide

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Chemical Properites
Mol. Formula :
C22H18F4N4O2S
Mol. Weight :
478.46
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : N-Methyl enzalutamide is an impurity of Enzalutamide (Enzalutamide impurity 1), which is an androgen-receptor (AR) antagonist for the treatment for prostate cancer.

References : Tran C. et al.: Science, 324(5928), 787-790, 2009; Scher H. I. et al.: Lancet.,375(9724), 1437-1446, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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