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N,N-Didesmethyl ulipristal

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N,N-Didesmethyl ulipristal, >98%

CAS No. : [244206-52-8]

MDL No. : MFCD23160310

Synonyms : 11β-(4-Aminophenyl)-17α-hydroxy-19-norpregna-4,9-diene-3,20-dione

IUPAC Name : (8S,11R,13S,14S,17R)-17-Acetyl-11-(4-aminophenyl)-17-hydroxy-13-methyl-1,2,6,7,8,11,12,13,14,15,16,17-dodecahydro-3H-cyclopenta[a]phenanthren-3-one

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Chemical Properites
Mol. Formula :
C26H31NO3
Mol. Weight :
405.53
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
DCM
For Laboratory research use only, not for drug, household or other uses.

Applications : N,N-Didesmethyl ulipristal is the N,N-didemethylated analog and metabolite of the Ulipristal acetate, which is a novel selective progesterone receptor modulator (SPRM) for the treatment of benign gynecological conditions such as uterine myoma.

References : Ciarmela P. et al.: Reprod Sci., 21(9), 1120-1125, 2014; Munuce M. J. et al.: Eur. J. Contracept Reprod Health Care. 18(5), 355-363, 2013; Pohl O. et al.: Curr Drug Saf. 8(2), 77-97, 2013; Pohl O. et al.: Regul Toxicol Pharmacol. 66(1) 6-12, 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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